The school was established in 1980 by a small group of concerned Christians who sensed the need for an Armenian Christian school. The first location of the school was in a church basement in Pasadena. Sahag-Mesrob is a non-denominational school. The school is not affiliated with any church or organization.
Sahag-Mesrob has been at its present location since 1983. Mr. John Sheen (Hagop Geuvkalayjian) became the school’s generous benefactor by contributing the funds needed to purchase the school property. The new building was constructed in September 1987.